Upgrading Indiana Jones in “Indiana Jones and the Great Circle” to its full potential can be challenging and requires strategic planning, as the game’s health and stamina upgrade system is complex and involves multiple steps. Here is a detailed overview on how to fully upgrade Indiana Jones in one playthrough:

### Step 1: Understand the Upgrade System
The game has a system where you can upgrade Indiana Jones’s health and stamina using Medicine Bottles and Adventure Points. Each upgrade requires specific items and points.

### Step 2: Find Medicine Bottles
Medicine Bottles are scattered around the game world, often in obscure areas. You need to collect these bottles to upgrade your health and stamina.

### Step 3: Complete Quests for Free Upgrades
In Valeria, you will receive the quest “A Remedy For All,” which allows you to receive a free stamina or health upgrade after finding all the medicine bottles scattered around the town. This quest should be completed before the main storyline takes you out of the Vatican City area.

### Step 4: Use Medicine Bottles to Upgrade
Each Medicine Bottle can be used to upgrade your health and stamina. There are three distinct level upgrades for health and stamina, and each upgrade requires a specific number of Medicine Bottles. The Moxie and Shaping Up books each cost five Medicine Bottles, with the first of each book requiring 300 Adventure Points to redeem.

### Step 5: Acquire Adventure Points
Adventure Points are earned through various activities in the game, such as completing quests, solving puzzles, and exploring the environment. You will need these points to redeem the Moxie and Shaping Up books, which are crucial for permanent HP boosts.

### Step 6: Upgrade Using Books
– **Moxie Book**: This book costs 5 Medicine Bottles and provides a health upgrade.
– **Shaping Up Book**: This book also costs 5 Medicine Bottles initially but requires more bottles for subsequent upgrades (10 and 15 Medicine Bottles for the second and third upgrades, respectively). Each book upgrade provides additional HP bars.

### Step 7: Manage Your Progress
Given the complexity of the upgrade system, it’s essential to manage your progress carefully. Make sure you have enough Medicine Bottles and Adventure Points before attempting to upgrade. You can temporarily increase your HP by consuming food items like bread and crackers, but these are only temporary boosts.

### Conclusion
While it is possible to fully upgrade Indiana Jones in one playthrough, it requires meticulous planning and resource management. You need to collect Medicine Bottles, complete quests for free upgrades, earn Adventure Points, and strategically use these resources to upgrade your health and stamina using the Moxie and Shaping Up books.

By following these steps, you can ensure that Indiana Jones is fully upgraded by the end of your playthrough, allowing you to tackle challenges more effectively and enjoy the game’s rich content without limitations.